TY - JOUR
T1 - A comparison of the double hydrodistention implantation technique (HIT) and the HIT with a polyacrylate/polyalcohol copolymer (PPC) for the endoscopic treatment of primary vesicoureteral reflux
AU - Akin, Melih
AU - Erginel, Basak
AU - Karadag, Cetin Ali
AU - Yildiz, Abdullah
AU - Özçelik, Gül Sumru
AU - Sever, Nihat
AU - Genc, Nimetullah Mete
AU - Dokucu, Ali Ihsan
N1 - Publisher Copyright:
© 2014, Springer Science+Business Media Dordrecht.
PY - 2014/10/25
Y1 - 2014/10/25
N2 - Objectives: We aimed to compare the success rates of the double hydrodistention implantation technique (HIT) and the HIT with a polyacrylate/polyalcohol copolymer (PPC) for the treatment of primary vesicoureteral reflux (VUR) with a new nonbiodegradable tissue-augmenting substance (Vantris, Promedon, Cordoba, Argentina).Methods: Between January 2011 and December 2012, fifty-two children who underwent subureteric injection for primary VUR are included. The children were randomly separated into two groups, the HIT and the double HIT groups, according to the type of injection. Success was defined as no reflux on a follow-up voiding cystourethrogram (VCUG) after 6 months. The patients were evaluated according to sex, age, grade of reflux, number of injections, and injected volume, and the radiological success rates were compared.Results: Fifty-two patients underwent an endoscopic injection for primary grade III–V VUR. The HIT group consisted of 26 patients with 33 ureters, and the double HIT group consisted of 26 patients with 35 ureters. There were no significant differences in terms of the sex, ages, VUR grades, bilaterality between the two groups. The mean injected volumes were ml 1.12 (1.02–1.22) in the HIT group and 1.24 ml (95 % CI 1.10–1.38) in the double HIT group. The reflux was resolved in 21/33 (63.6 %) ureters in the HIT group and in 30/35 (85.7 %) ureters in the double HIT group, (p < 0.05). We had only one complication. This patient in the double HIT group, developed bilateral hydronephrosis and oliguric renal failure requiring open reimplantation at the sixth month.Conclusion: We observed successful results double HIT method with PPC in Grade III–V reflux, but the long-term follow-up of patients is needed for hydronephrosis. As the double HIT treatment leads to a higher success rate, its use is preferable.
AB - Objectives: We aimed to compare the success rates of the double hydrodistention implantation technique (HIT) and the HIT with a polyacrylate/polyalcohol copolymer (PPC) for the treatment of primary vesicoureteral reflux (VUR) with a new nonbiodegradable tissue-augmenting substance (Vantris, Promedon, Cordoba, Argentina).Methods: Between January 2011 and December 2012, fifty-two children who underwent subureteric injection for primary VUR are included. The children were randomly separated into two groups, the HIT and the double HIT groups, according to the type of injection. Success was defined as no reflux on a follow-up voiding cystourethrogram (VCUG) after 6 months. The patients were evaluated according to sex, age, grade of reflux, number of injections, and injected volume, and the radiological success rates were compared.Results: Fifty-two patients underwent an endoscopic injection for primary grade III–V VUR. The HIT group consisted of 26 patients with 33 ureters, and the double HIT group consisted of 26 patients with 35 ureters. There were no significant differences in terms of the sex, ages, VUR grades, bilaterality between the two groups. The mean injected volumes were ml 1.12 (1.02–1.22) in the HIT group and 1.24 ml (95 % CI 1.10–1.38) in the double HIT group. The reflux was resolved in 21/33 (63.6 %) ureters in the HIT group and in 30/35 (85.7 %) ureters in the double HIT group, (p < 0.05). We had only one complication. This patient in the double HIT group, developed bilateral hydronephrosis and oliguric renal failure requiring open reimplantation at the sixth month.Conclusion: We observed successful results double HIT method with PPC in Grade III–V reflux, but the long-term follow-up of patients is needed for hydronephrosis. As the double HIT treatment leads to a higher success rate, its use is preferable.
KW - Double hydrodistention implantation technique
KW - Hydrodistention implantation technique
KW - Polyacrylate/polyalcohol copolymer
KW - Vesicoureteral reflux
UR - http://www.scopus.com/inward/record.url?scp=84910015730&partnerID=8YFLogxK
U2 - 10.1007/s11255-014-0771-5
DO - 10.1007/s11255-014-0771-5
M3 - Article
C2 - 24966099
AN - SCOPUS:84910015730
SN - 0301-1623
VL - 46
SP - 2057
EP - 2061
JO - International Urology and Nephrology
JF - International Urology and Nephrology
IS - 11
ER -