Brachial embolism from mechanical mitral valve thrombosis: Multimodality imaging-guided successful thrombolysis

Sinan Cerşit; Emrah Bayam; Sabahattin Gündüz; Ahmet Güner; Mehmet Özkan

doi:10.1097/MBC.0000000000000696

Brachial embolism from mechanical mitral valve thrombosis: Multimodality imaging-guided successful thrombolysis

Sinan Cerşit, Emrah Bayam, Sabahattin Gündüz, Ahmet Güner, Mehmet Özkan

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

We report the administration of low-dose (25 mg) prolonged infusion (25 h) of tissue-typed plasminogen activator (t-PA) in the treatment of brachial arterial thromboembolism (BAT) secondary to prosthetic valve thrombosis (PVT), under the guidance of multimodality imaging. BAT is a rare disorder with serious consequences. The case of BAT secondary to mitral PVT was successfully treated with low-dose prolonged infusion of t-PA under the guidance of multimodality imaging with upper extremity duplex Doppler ultrasonography, multislice computerized tomographic angiography, coventional angiography and advanced transesophageal echocardiography. This case has demonstrated that low-dose prolonged infusion of t-PA may be adequate in the treatment of BAT.

Original language	English
Pages (from-to)	395-398
Number of pages	4
Journal	Blood Coagulation and Fibrinolysis
Volume	29
Issue number	4
DOIs	https://doi.org/10.1097/MBC.0000000000000696
Publication status	Published - 1 Jun 2018

Keywords

brachial artery
computed tomography
prosthetic mitral valve
thromboembolism
thrombolytic therapy
two-dimensional and three-dimensional transesophageal echocardiography

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10.1097/MBC.0000000000000696

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title = "Brachial embolism from mechanical mitral valve thrombosis: Multimodality imaging-guided successful thrombolysis",

abstract = "We report the administration of low-dose (25 mg) prolonged infusion (25 h) of tissue-typed plasminogen activator (t-PA) in the treatment of brachial arterial thromboembolism (BAT) secondary to prosthetic valve thrombosis (PVT), under the guidance of multimodality imaging. BAT is a rare disorder with serious consequences. The case of BAT secondary to mitral PVT was successfully treated with low-dose prolonged infusion of t-PA under the guidance of multimodality imaging with upper extremity duplex Doppler ultrasonography, multislice computerized tomographic angiography, coventional angiography and advanced transesophageal echocardiography. This case has demonstrated that low-dose prolonged infusion of t-PA may be adequate in the treatment of BAT.",

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T1 - Brachial embolism from mechanical mitral valve thrombosis

T2 - Multimodality imaging-guided successful thrombolysis

AU - Cerşit, Sinan

AU - Bayam, Emrah

AU - Gündüz, Sabahattin

AU - Güner, Ahmet

AU - Özkan, Mehmet

PY - 2018/6/1

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N2 - We report the administration of low-dose (25 mg) prolonged infusion (25 h) of tissue-typed plasminogen activator (t-PA) in the treatment of brachial arterial thromboembolism (BAT) secondary to prosthetic valve thrombosis (PVT), under the guidance of multimodality imaging. BAT is a rare disorder with serious consequences. The case of BAT secondary to mitral PVT was successfully treated with low-dose prolonged infusion of t-PA under the guidance of multimodality imaging with upper extremity duplex Doppler ultrasonography, multislice computerized tomographic angiography, coventional angiography and advanced transesophageal echocardiography. This case has demonstrated that low-dose prolonged infusion of t-PA may be adequate in the treatment of BAT.

AB - We report the administration of low-dose (25 mg) prolonged infusion (25 h) of tissue-typed plasminogen activator (t-PA) in the treatment of brachial arterial thromboembolism (BAT) secondary to prosthetic valve thrombosis (PVT), under the guidance of multimodality imaging. BAT is a rare disorder with serious consequences. The case of BAT secondary to mitral PVT was successfully treated with low-dose prolonged infusion of t-PA under the guidance of multimodality imaging with upper extremity duplex Doppler ultrasonography, multislice computerized tomographic angiography, coventional angiography and advanced transesophageal echocardiography. This case has demonstrated that low-dose prolonged infusion of t-PA may be adequate in the treatment of BAT.

KW - brachial artery

KW - computed tomography

KW - prosthetic mitral valve

KW - thromboembolism

KW - thrombolytic therapy

KW - two-dimensional and three-dimensional transesophageal echocardiography

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Brachial embolism from mechanical mitral valve thrombosis: Multimodality imaging-guided successful thrombolysis

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