Early Thrombosis of a Mitral Annuloplasty Ring in a Patient with MTHFR and Factor V Leiden Mutations

Sinan Cerşit, Emrah Bayam, Sabahattin Gündüz, Mehmet Özkan

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Mitral annuloplasty ring thrombosis is an extremely infrequent pathology, for which no evidence-based antithrombotic management has yet been described. Herein is presented a case of heterozygous Factor V Leiden (FVL) and hyperhomocysteinemia with homozygous methylenetetrahydrofolate reductase (MTHFR) mutations that caused early thrombosis of the mitral annuloplasty ring. The clinical management and antithrombotic treatment of the patient, and the implications of hyperhomocysteinemia, are discussed. Video 1: Mobile 9-mm thrombus of mitral annuloplasty ring on two-dimensional (2D) transesophageal echocardiography. Video 2: Mitral annuloplasty ring thrombus on real time three-dimensional (RT-3D) transesophageal echocardiography. Video 3: 2D video showing the morphologic change of mitral annuloplasty ring thrombus after prolonged UFH infusion.

Original languageEnglish
Pages (from-to)585-588
Number of pages4
JournalJournal of Heart Valve Disease
Volume26
Issue number5
Publication statusPublished - 1 Sept 2017
Externally publishedYes

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