Lung transplantation for silicosis

Merih Kalamanoglu Balci, Mustafa Vayvada, Cemal Asım Kutlu

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Aim: Silicosis is an occupational disease caused by inhalation of silica dust. In terms of lung transplantation, silicosis has not been a well-documented disease. This article reports the perioperative course and the outcome of patients affected by silicosis. Material and Method: Single lung transplantation was performed in 5 of 77 patients diagnosed with silicosis, who comprised 6.4% of all lung transplantations during the same period. All the patients were males, with an age range of 34–41 years. Of the five patients, two were dental technicians, one was a quarry worker, and the remaining two patients were jeans sandblasting workers. All the patients had dyspnea that required oxygen during rest. Results: Unilateral lung transplantation was performed in four patients for the right lung and in one patient for the left lung. All the patients were approached by anterior thoracotomy. In one patient, a sternum transverse incision was made to take control over the right main pulmonary artery. Arteriovenous extracorporeal membrane oxygenation support was required for two patients due to hemodynamic instability during the operation. There was no perioperative mortality. Two cases were extubated in the first 24 hours, and tracheostomy was performed in one patient because of prolonged intubation. Three patients were discharged from the hospital on days 9, 21, and 28. Discussion: Lung transplantation is the only curative treatment for end-stage silicosis. Removal of the native lung may be extremely difficult. Dense pleural adhesions and fibrotic hilar lymph nodes must be assessed at the preoperative CT scan of the thorax.

Translated title of the contributionSilikozisde akciğer transplantasyonu
Original languageEnglish
Pages (from-to)155-159
Number of pages5
JournalJournal of Clinical and Analytical Medicine
Volume8
DOIs
Publication statusPublished - 2017
Externally publishedYes

Keywords

  • ECMO
  • Lung transplantation
  • Silicosis

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