Multiple system atrophy (MSA-C) presenting with cognitive affective cerebellar syndrome and psychosis

Asli Demirtaş Tatlidede, Haşmet A. Hanaǧasi, Murat Çabalar, Vildan Yayla

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Besides its well-established motor functions, the modulatory role of cerebellum in the neural networks subserving cognition and emotion has been supported by several lines of evidence obtained from neuroanatomical investigations, functional neuroimaging and clinical research. Damage to cerebellar posterior lobe and vermis may lead to a cognitive affective cerebellar syndrome primarily comprising cognitive disorders characterized by executive dysfunctioning, language and visuospatial impairments in addition to disorders of affect and other psychiatric impairments. Cognitive and affective symptoms have often been reported in neurodegenerative cerebellar diseases while psychotic symptoms occur less frequently. In this article, we describe an extraordinary case of multiple system atrophy (MSA-C), who presented with cognitive affective cerebellar syndrome and psychotic symptoms before cerebellar ataxia was evident. The wide variety of symptoms observed in this case underlines the critical role of cerebellum in modulation of networks engaged in cognition, affect, thought and perception, and provides further evidence regarding the contribution of cerebellar dysfunction to several neuropsychiatric symptoms.

Translated title of the contributionKognitif affektif serebellar sendrom ve psikoz bulguları ile ortaya çıkan bir multisistem atrofi (MSA-C) olgusu
Original languageEnglish
Pages (from-to)107-110
Number of pages4
JournalTurk Noroloji Dergisi
Volume19
Issue number3
DOIs
Publication statusPublished - 2013
Externally publishedYes

Keywords

  • Cerebellum
  • Cognitive affective cerebellar syndrome
  • Multiple system atrophy
  • Psychosis

Fingerprint

Dive into the research topics of 'Multiple system atrophy (MSA-C) presenting with cognitive affective cerebellar syndrome and psychosis'. Together they form a unique fingerprint.

Cite this