Neurodevelopmental influences in psychosis: A case of left cerebral hemiatrophy and schizoaffective disorder

Asli Demirtas Tatlidede, Ayse Destina Yalcin, Tugba Guven Canpolat

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Cerebral hemiatrophy (or Dyke-Davidoff-Masson Syndrome) is a neurodevelopmental disorder characterized by atrophy or hypoplasia of one cerebral hemisphere accompanied by ipsilateral calvarial changes. Clinically, the condition presents with contralateral motor dysfunction, facial asymmetry, epilepsy and intellectual impairment. Psychiatric manifestations are uncommon and the neuropsychiatric aspect of the disease is not well described. Here, we report a 26-year-old female who presented with left cerebral hemiatrophy and schizoaffective disorder. We discuss the relevance of left-sided neurodevelopmental cerebral atrophy in the context of disrupted neural development of brain lateralization, plasticity, and evidence regarding left hemisphere dysfunction in schizophrenia and schizoaffective disorder.

Translated title of the contributionPsikozda nörogelişimsel etkiler: Bir olgu nedeniyle sol serebral hemiatrofi ve şizoaffektif bozukluk
Original languageEnglish
Pages (from-to)368-372
Number of pages5
JournalKlinik Psikofarmakoloji Bulteni
Volume23
Issue number4
DOIs
Publication statusPublished - 2013
Externally publishedYes

Keywords

  • Cerebral hemiatrophy
  • Dyke-davidoff-masson syndrome
  • Schizophrenia and disorders with psychotic features

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