No harmful effect of dialysis-induced hypotension on the myocardium in patients who have normal ejection fraction and a negative exercise test

Hakan Fotbolcu, Vecih Oduncu, Emre Gürel, Cihan Cevik, Ayhan Erkol, Kivilcim Özden, Bahtisen Guven, Akin Dayan, Gökçe Şirin, Yelda Basaran

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Background: We investigated the effects of dialysis-induced hypotension (DIH) on the myocardium of patients who have a normal ejection fraction and normal treadmill stress tests. Methods: This study included 26 end-stage renal disease (ESRD) patients with DIH, 30 ESRD patients without DIH (non-DIH), and 30 control subjects. Mitral-myocardial systolic velocity (MSV), the mitral E′/A′ ratio, the left ventricle filling pressure index (E/E′ ratio), tricuspid-MSV, and the tricuspid E′/A′ ratio were calculated. Results: Biventricular systolic and diastolic functions were impaired in dialysis patients. The mitral and tricuspid MSV were similar between DIH and non-DIH patients (8.03 ± 0.90 cm/s vs. 8.31 ± 1.68 cm/s, p = 0.896, and 13.27 ± 2.97 cm/s vs. 13.15 ± 2.37 cm/s, p = 0.980). Mitral and tricuspid E′/A′ were similar between DIH and non-DIH patients. (1.30 ± 0.53 vs. 1.16 ± 0.56, p = 0.695, and 0.70 ± 0.24 vs. 0.68 ± 0.33, p = 0.976). Likewise, the E/E′ ratio was similar between DIH and non-DIH patients (8.20 ± 2.83 vs. 8.28 ± 2.53, p = 0.990). Conclusion: Although biventricular systolic and diastolic function is impaired in dialysis patients compared to controls, DIH episodes did not have an adverse effect on the myocardial functions.

Original languageEnglish
Pages (from-to)671-677
Number of pages7
JournalKidney and Blood Pressure Research
Volume35
Issue number6
DOIs
Publication statusPublished - Feb 2013
Externally publishedYes

Keywords

  • Biventricular systolic and diastolic functions
  • Dialysis-induced hypotension
  • Ejection fraction

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