TY - JOUR
T1 - Perception and management of cancer predisposition in pediatric cancer centers
T2 - A European-wide questionnaire-based survey
AU - LEGEND-COST Working group 5 members
AU - Lazic, Jelena
AU - Haas, Oskar A.
AU - Özbek, Ugur
AU - Ripperger, Tim
AU - Byrjalsen, Anna
AU - te Kronnie, Geertruij
AU - Sayitoğlu, Muge
AU - Ng, Ozden Hatirnaz
AU - Agaoglu, Nihat Bugra
AU - Erbilgin, Yucel
AU - Senturk, Gizem
AU - Khodzhoev, Khusan
AU - Sudutan, Tugce
AU - Altıner, Sule
AU - Ozdemir, Gul Nihal
AU - Demirsoy, Ugur
AU - Yilmaz, Ceren Damla
AU - Ruml, Jelena
AU - Yalcin, Koray
AU - Ili, Ezgi Gökpinar
AU - Pantic, Ivana
AU - Vukovic, Milica
AU - Mlynarski, Wojciech
AU - Pastorczak, Agata
AU - Bosch, Jutte van der Werff Ten
AU - Schlegelberger, Brigitte
AU - Slamova, Lucie
AU - Loeffen, Jan
AU - Garcia-Orad, Africa
AU - Metzler, Markus
AU - Reismüller, Bettina
N1 - Publisher Copyright:
© 2023 Wiley Periodicals LLC.
PY - 2023/5
Y1 - 2023/5
N2 - The European Union-funded COST Action (LEukaemia GENe Discovery by data sharing, mining, and collaboration) LEGEND was an international and multidisciplinary collaboration between clinicians and researchers that covered a range of aspects of genetic predisposition in childhood leukemia. Within this framework, we explored the perception and handling of genetic predisposition in the daily practice of European treatment centers. Herein, we present the results of our questionnaire-based survey. We found that the overall awareness is quite high, and respondents remarked that identification and treatment of the most common predisposition syndromes were present. Nevertheless, high demand for continuous education and routinely updated resources remains.
AB - The European Union-funded COST Action (LEukaemia GENe Discovery by data sharing, mining, and collaboration) LEGEND was an international and multidisciplinary collaboration between clinicians and researchers that covered a range of aspects of genetic predisposition in childhood leukemia. Within this framework, we explored the perception and handling of genetic predisposition in the daily practice of European treatment centers. Herein, we present the results of our questionnaire-based survey. We found that the overall awareness is quite high, and respondents remarked that identification and treatment of the most common predisposition syndromes were present. Nevertheless, high demand for continuous education and routinely updated resources remains.
KW - cancer genetics
KW - germ cell tumor
KW - pediatric hematology/oncology
UR - http://www.scopus.com/inward/record.url?scp=85149467823&partnerID=8YFLogxK
U2 - 10.1002/pbc.30229
DO - 10.1002/pbc.30229
M3 - Article
C2 - 36860090
AN - SCOPUS:85149467823
SN - 1545-5009
VL - 70
JO - Pediatric Blood and Cancer
JF - Pediatric Blood and Cancer
IS - 5
M1 - e30229
ER -
