TY - GEN
T1 - Bioimpedance Spectroscopy in Subjects with Auricular Vagus Nerve Stimulation
AU - Ülgen, Y.
AU - Büyüksaraç, B.
AU - Tunç, B.
AU - Solmaz, H.
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/6
Y1 - 2019/6
N2 - In this paper, single side body impedance spectroscopy is performed between wrist and ankle in response to auricular transcutaneous electrical vagus stimulation, to obtain the Cole parameters Ro, R∞ and fc. Following a resting period of 5 minutes in supine position, left ear vagus nerve was stimulated for 3 minutes and BIS performed every 10 seconds, on 8 healthy subjects with age: 23,6±1,5 years, height: 175±8,3 cm; weight: 69,5±18,7 kg and BMI: 22,6±5,5 kg/cm2. Cole circles moved to the right (inreased Ro and R∞) with stimulation while the centers shifted upwards. Intracellular and extracellular resistances and the capacitance Cm all increased at the onset of vagus stimulation; resulting in a decrease of 3,4±1.33% in fc. Changes in Ri mainly indicate water shift between cells and extracellular fluid; physiological changes occurred on cell membrane. fc independent of the participants' anthropomorphic factors could be used as an indicator to vagus nerve stimulation, without further normalization. This preliminary study was realized with a limited number of participants; however, to reach statistically meaningful results measurements will be performed over a larger sample size.
AB - In this paper, single side body impedance spectroscopy is performed between wrist and ankle in response to auricular transcutaneous electrical vagus stimulation, to obtain the Cole parameters Ro, R∞ and fc. Following a resting period of 5 minutes in supine position, left ear vagus nerve was stimulated for 3 minutes and BIS performed every 10 seconds, on 8 healthy subjects with age: 23,6±1,5 years, height: 175±8,3 cm; weight: 69,5±18,7 kg and BMI: 22,6±5,5 kg/cm2. Cole circles moved to the right (inreased Ro and R∞) with stimulation while the centers shifted upwards. Intracellular and extracellular resistances and the capacitance Cm all increased at the onset of vagus stimulation; resulting in a decrease of 3,4±1.33% in fc. Changes in Ri mainly indicate water shift between cells and extracellular fluid; physiological changes occurred on cell membrane. fc independent of the participants' anthropomorphic factors could be used as an indicator to vagus nerve stimulation, without further normalization. This preliminary study was realized with a limited number of participants; however, to reach statistically meaningful results measurements will be performed over a larger sample size.
KW - bioimpedance spectroscopy
KW - extracellular and intracellular body fluids
KW - transcutaneous vagus nerve stimulation
UR - http://www.scopus.com/inward/record.url?scp=85071726175&partnerID=8YFLogxK
U2 - 10.1109/MeMeA.2019.8802168
DO - 10.1109/MeMeA.2019.8802168
M3 - Conference contribution
AN - SCOPUS:85071726175
T3 - Medical Measurements and Applications, MeMeA 2019 - Symposium Proceedings
BT - Medical Measurements and Applications, MeMeA 2019 - Symposium Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2019 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2019
Y2 - 26 June 2019 through 28 June 2019
ER -