TY - GEN
T1 - Design of a cole-cole meter for complex impedance measurement of living tissues
AU - Solmaz, H.
AU - Ülgen, Y.
AU - Tümer, M.
PY - 2010
Y1 - 2010
N2 - Measurement of complex impedance of biological systems is gaining wide popularity in determining the pathological and physiological status of tissues in research areas such as; body fat content, blood freshness, tissue ischemia, skin hydration, and etc. In this paper, we designed a four-probe, multi-frequency impedance meter for quick assessment of the viability of erythrocyte suspensions under storage conditions. Impedance measurements are based on magnitude-ratio and phase-difference detection principles. The system is built around a sine-wave generator, a voltage controlled current source, a phase-gain detector and a microcontroller unit. Device accuracy is checked against the HP 4284A LCR meter under different RC test loads that simulate physiological measurements. As a novelty, Cole-Cole parameters namely R 0, R∞, fc, α and the extracellular fluid and intracellular fluid resistances, Re and Ri are directly displayed in the same device, for the ease of use.
AB - Measurement of complex impedance of biological systems is gaining wide popularity in determining the pathological and physiological status of tissues in research areas such as; body fat content, blood freshness, tissue ischemia, skin hydration, and etc. In this paper, we designed a four-probe, multi-frequency impedance meter for quick assessment of the viability of erythrocyte suspensions under storage conditions. Impedance measurements are based on magnitude-ratio and phase-difference detection principles. The system is built around a sine-wave generator, a voltage controlled current source, a phase-gain detector and a microcontroller unit. Device accuracy is checked against the HP 4284A LCR meter under different RC test loads that simulate physiological measurements. As a novelty, Cole-Cole parameters namely R 0, R∞, fc, α and the extracellular fluid and intracellular fluid resistances, Re and Ri are directly displayed in the same device, for the ease of use.
KW - Bioimpedance
KW - Cole-cole parameters
KW - Magnitude-ratio and phase-difference detection
UR - http://www.scopus.com/inward/record.url?scp=79953814539&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:79953814539
SN - 9780889868250
T3 - Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010
SP - 208
EP - 211
BT - Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 2010
T2 - 7th IASTED International Conference on Biomedical Engineering, BioMED 2010
Y2 - 17 February 2010 through 19 February 2010
ER -