TY - JOUR
T1 - SARS-CoV-2 isolation and propagation from turkish COVID-19 patients
AU - Taştan, Cihan
AU - Yurtsever, Bulut
AU - Sir Karakuş, Gözde
AU - Dilek Kançaği, Derya
AU - Demir, Sevda
AU - Abanuz, Selen
AU - Seyis, Utku
AU - Yildirim, Mülazim
AU - Kuzay, Recai
AU - Elibol, Ömer
AU - Arbak, Serap
AU - Açikel Elmas, Merve
AU - Birdoğan, Selçuk
AU - Sezerman, Osman Uğur
AU - Kocagöz, Ayşe Sesin
AU - Yalçin, Koray
AU - Ovali, Ercüment
N1 - Publisher Copyright:
© TÜBİTAK.
PY - 2020
Y1 - 2020
N2 - The novel coronavirus pneumonia, which was named later as coronavirus disease 2019 (COVID-19), is caused by the severe acute respiratory syndrome coronavirus 2, namely SARS-CoV-2. It is a positive-strand RNA virus that is the seventh coronavirus known to infect humans. The COVID-19 outbreak presents enormous challenges for global health behind the pandemic outbreak. The first diagnosed patient in Turkey has been reported by the Republic of Turkey Ministry of Health on March 11, 2020. In May, over 150,000 cases in Turkey, and 5.5 million cases around the world have been declared. Due to the urgent need for a vaccine and antiviral drug, isolation of the virus is crucial. Here, we report 1 of the first isolation and characterization studies of SARS-CoV-2 from nasopharyngeal and oropharyngeal specimens of diagnosed patients in Turkey. This study provides an isolation and replication methodology,and cell culture tropism of the virus that will be available to the research communities.
AB - The novel coronavirus pneumonia, which was named later as coronavirus disease 2019 (COVID-19), is caused by the severe acute respiratory syndrome coronavirus 2, namely SARS-CoV-2. It is a positive-strand RNA virus that is the seventh coronavirus known to infect humans. The COVID-19 outbreak presents enormous challenges for global health behind the pandemic outbreak. The first diagnosed patient in Turkey has been reported by the Republic of Turkey Ministry of Health on March 11, 2020. In May, over 150,000 cases in Turkey, and 5.5 million cases around the world have been declared. Due to the urgent need for a vaccine and antiviral drug, isolation of the virus is crucial. Here, we report 1 of the first isolation and characterization studies of SARS-CoV-2 from nasopharyngeal and oropharyngeal specimens of diagnosed patients in Turkey. This study provides an isolation and replication methodology,and cell culture tropism of the virus that will be available to the research communities.
KW - COVID-19
KW - Coronavirus
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85086888515&partnerID=8YFLogxK
U2 - 10.3906/biy-2004-113
DO - 10.3906/biy-2004-113
M3 - Article
AN - SCOPUS:85086888515
SN - 1300-0152
VL - 44
SP - 192
EP - 202
JO - Turkish Journal of Biology
JF - Turkish Journal of Biology
IS - Special issue 1
ER -
