The frequency and fetomaternal outcomes of early-and late-onset preeclampsia: The experience of a single tertiary health center in the bustling metropolis of Turkey; Istanbul

The purpose of the study is to determine the prevalence preeclampsia and to evaluate the maternal and the fetal adverse outcomes in the severe and the early- onset preeclampsia subgroups. Hundred and sixteen pregnant women with preclampsia who gave birth in an academic tertiary health centre were included in this study. The preeclampsia rate was 1.4 per 100 singleton births for three years (1.5/100 in 2012 and 1.3/100 in both 2013 and 2014 in this study). The rates of severe and early- onset preeclampsia were found as 0.5 and 0.4 per 100 singleton births in this three years period. Adverse maternal outcomes occurred in 18 cases. Maternal mortality occurred in 1 case. In severe preeclampsia (PE), the mean gestational age (33. week), birth weight (1935 g) and Apgar score at 5th minute at delivery (6.8 points) were calculated. In severe PE, the admission rate to Neonatal Intensive Care Unit (NICU) and neonatal mortality rate were 67 % and 24%, respectively. In the early- onset preeclampsia, the mean birth weight and 5th min- Apgar score at delivery were found as 1454 g and 5.4 points, respectively. The admission rate to NICU and neonatal mortality rate were 91% and %30 in early-onset PE, respectively. The rate of severe PE in the early- onset PE was 59%. The women with severe preeclampsia had the highest antihypertensive drug prescribing rate (41%) at discharge. Preeclampsia, particularly early- onset and severe preeclampsia require special attention of the healthcare providers.