Wilms' tumor: A 24-year retrospective study from a single center

Başak Erginel, Sema Vural, Melih Akin, Çetin Ali Karadaǧ, Nihat Sever, Abdullah Yildiz, Canan Tanik, Arzu Ataman Demir, Özlem Yanar, Ali Ihsan Dokucu

Araştırma sonucu: Dergi katkısıMakalebilirkişi

13 Alıntılar (Scopus)

Özet

Medical records of 71 children with Wilms' tumor at Sisli Etfal Education and Research Hospital between 1990 and 2014 were reviewed. Mean age at diagnosis was 3.11 years (2 days-7 years). Male to female ratio was M/F = 6/10. The incidence of associated anomaly was 16.9%. Clinical manifestations included abdominal mass (89%), hematuria (30%), hypertansion (25%), abdominal pain (15%), fever (5%), restlessness (2%), weight loss (2%), varicocele (1%). Ultrasound (USG) was the most often initial study in a child presenting with abdominal mass. Doppler USG was also made to evaluate the inferior vena cava (IVC) for the presence of tumor extension in children with renal mass. The left kidney was affected in 33 patients (46.5%), the right was affected in 31 patients (43.7%). Two patients was extrarenal (2.8%). And 5 patients (7.04%) were bilateral on the presentation. Preoperative chemotheraphy was done in 14 cases. In 63 patients with unilateral Wilm tm, unilateral radical nefrectomy is performed. In one patient with solitary kidney, nephron sparing surgery (NSS) is performed. In 3 patients with bilateral tm NSS is performed and in 2 patients with bilateral Wilms' tm NSS is performed in one side and nefrectomy on the other side. Out of 71 Wilms tumor (WT) patients, 17 of them has been out of our follow. And 4 of them are died. Ten of them has metastases. Forty children are under follow with no metastases. Patients with WT needs a multimodal, multidisiplinary treatment with the cooperation of pediatric oncologist and pediatric surgeon and needs close follow-up.

Orijinal dilİngilizce
Sayfa (başlangıç-bitiş)409-414
Sayfa sayısı6
DergiPediatric Hematology and Oncology
Hacim31
Basın numarası5
DOI'lar
Yayın durumuYayınlanan - Ağu 2014
Harici olarak yayınlandıEvet

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